Article
Functional and clinical consequences of Fc receptor polymorphic and copy number variants.
Clinical and experimental immunology - 1 Aug 2009
Bournazos S, Woof J M, Hart S P, Dransfield I
Abstract excerpt
Receptors for immunoglobulins (Fc receptors) play a central role during an immune response, as they mediate the specific recognition of antigens of almost infinite diversity by leucocytes, thereby linking the humoral and cellular components of immunity. Indeed, engagement of Fc receptors by immunoglobulins initiates a range of immunoregulatory processes that might also play a role in disease pathogenesis. In the...
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