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Article

Synonymous nucleotide substitutions in the neonatal Fc receptor.

Immunogenetics - 1 May 2002

Gunraj Carolyn A, Fernandes Bernard J, Denomme Gregory A

Abstract excerpt

The neonatal Fc receptor (FcRn) is a key receptor involved in the transcytosis of IgG across the maternal-fetal barrier. The level of IgG varies considerably among newborn infants. Since other Fc gamma receptors show single nucleotide functional variants, we determined whether common variant alleles exist for the FcRn. Direct sequence analysis was performed on PCR-amplified complementary DNA (cDNA) isolated from...

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Share to Histocompatibility Antigens Class I
Share to Polymorphism, Single Nucleotide
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PMID: 12037606
DOI: 10.1007/s00251-002-0449-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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