Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Oral poliovaccine: will it help eradicate polio or cause the next epidemic?

The Israel Medical Association journal : IMAJ - 1 May 2006

Shulman Lester M, Manor Yosef, Sofer Danit, Swartz Tiberio, Mendelson Ella

Abstract excerpt

BACKGROUND: Poliovirus rapidly evolves by nucleic acid substitutions and genetic recombination with other polioviruses and non-polio enteroviruses. Evolving oral poliovaccine can rapidly revert to neurovirulence and undergo antigenic alterations. OBJECTIVES: To evaluate the threat of vaccine-derived poliovirus (1-15% divergence from the respective Sabin strain) for a poliomyelitis-free population in a country...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibodies, Viral
Share to Enterovirus
Share to Infant

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Poliomyelitis

Share to Poliovirus

Share to Poliovirus Vaccine, Oral

Share to Recombination, Genetic

Share to Sewage

Source

Identifiers

PMID: 16805227

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Oral poliovaccine: will it help eradicate polio or cause the next epidemic?PMID 16805227Read ↗

Molecular and antigenic characterization of a highly evolved derivative of the type 2 oral poliovaccine strain isolated from sewage in Israel.Semantic proximity Read ↗

Evolution of the Sabin Vaccine into Pathogenic Derivatives without Appreciable Changes in Antigenic Properties: Need for Improvement of Current Poliovirus SurveillanceSemantic proximity Read ↗

Genetic stabilization of attenuated oral vaccines against poliovirus types 1 and 3Semantic proximity Read ↗

VACCINE-DERIVED POLIOVIRUSES AND THE ENDGAME STRATEGY FOR GLOBAL POLIO ERADICATIONSemantic proximity Read ↗

Developing genetically stable live-attenuated vaccine candidates against type 1 and 3 poliovirusSemantic proximity Read ↗

Sabin Vaccine Reversion in the Field: a Comprehensive Analysis of Sabin-Like Poliovirus Isolates in NigeriaSemantic proximity Read ↗

Vaccine-derived polioviruses.Semantic proximity Read ↗

Assessment of genetic changes and neurovirulence of shed Sabin and novel type 2 oral polio vaccine virusesSemantic proximity Read ↗

Spread of vaccine-derived poliovirus from a paralytic case in an immunodeficient child: an insight into the natural evolution of oral polio vaccine.Semantic proximity Read ↗

Engineering the Live-Attenuated Polio Vaccine to Prevent Reversion to VirulenceSemantic proximity Read ↗

Evolution of the Sabin type 1 poliovirus in humans: characterization of strains isolated from patients with vaccine-associated paralytic poliomyelitis.Semantic proximity Read ↗

From Vaccine to Pathogen: Modeling Sabin 2 Vaccine Virus Reversion and Evolutionary EpidemiologySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.