Article
Molecular and antigenic characterization of a highly evolved derivative of the type 2 oral poliovaccine strain isolated from sewage in Israel.
Journal of clinical microbiology - 1 Oct 2000
Shulman L M, Manor Y, Handsher R, Delpeyroux F, McDonough M J, Halmut T, Silberstein I, Alfandari J, Quay J, Fisher T, Robinov J, Kew O M, Crainic R, Mendelson E
Abstract excerpt
An unusual, highly diverged derivative of the Sabin type 2 oral poliovaccine (OPV) strain was recovered from environmental samples during routine screening for wild polioviruses. Virus was cultivated in L20B cells and then passaged on BGM cells at 40 degrees C (RCT [reproductive capacity at supra...
Topics
- 5' Untranslated Regions
- Adolescent
- Amino Acid Sequence
- Animals
- Antibodies, Viral
- Capsid
- Female
- Genetic Variation
- Humans
- Israel
- Male
- Mice
- Mice, Transgenic
- Mutation
