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Article

Molecular and antigenic characterization of a highly evolved derivative of the type 2 oral poliovaccine strain isolated from sewage in Israel.

Journal of clinical microbiology - 1 Oct 2000

Shulman L M, Manor Y, Handsher R, Delpeyroux F, McDonough M J, Halmut T, Silberstein I, Alfandari J, Quay J, Fisher T, Robinov J, Kew O M, Crainic R, Mendelson E

Abstract excerpt

An unusual, highly diverged derivative of the Sabin type 2 oral poliovaccine (OPV) strain was recovered from environmental samples during routine screening for wild polioviruses. Virus was cultivated in L20B cells and then passaged on BGM cells at 40 degrees C (RCT [reproductive capacity at supraoptimal temperature]-positive marker) to select against most OPV strains. All but 1 of 25 RCT-positive OPV-derived...

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Identifiers

PMID: 11015392
DOI: 10.1128/JCM.38.10.3729-3734.2000
PMCID: PMC87465

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PVR

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