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Article

Vaccine-derived polioviruses.

The Journal of infectious diseases - 1 Nov 2014

Burns Cara C, Diop Ousmane M, Sutter Roland W, Kew Olen M

Abstract excerpt

The attenuated oral poliovirus vaccine (OPV) has many properties favoring its use in polio eradication: ease of administration, efficient induction of intestinal immunity, induction of durable humoral immunity, and low cost. Despite these advantages, OPV has the disadvantage of genetic instability, resulting in rare and sporadic cases of vaccine-associated paralytic poliomyelitis (VAPP) and the emergence of...

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Identifiers

PMID: 25316847
DOI: 10.1093/infdis/jiu295

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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