Article
Electric potential induced dissociation of hybridized DNA with hairpin motif immobilized on silicon surface.
Langmuir : the ACS journal of surfaces and colloids - 4 Jul 2006
Wei Fang, Qu Peng, Zhai Lin, Chen Chunlai, Wang Haifang, Zhao Xin Sheng
Abstract excerpt
DNA probes were immobilized on silicon surfaces through ester condensation between the -COOH group on the surface and the terminal -OH group in the oligonucleotide, and the surface density of DNA probes against the concentration of immobilization solution was measured by radioactive labeling. The dissociation of DNA duplex on the surface by an electric potential was studied with the scanning potential hairpin...
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