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Article

Discriminating DNA mismatches by electrochemical and gravimetric techniques.

Biosensors & bioelectronics - 15 Oct 2013

Mazouz Zouhour, Fourati Najla, Zerrouki Chouki, Ommezine Asma, Rebhi Lamia, Yaakoubi Nourdin, Kalfat Rafik, Othmane Ali

Abstract excerpt

A silicon nitride functionalized electrode and a 104 MHz lithium tantalate (LiTaO₃) surface acoustic wave (SAW) sensor have been used to investigate target-probe recognition processes. Electrochemical and gravimetric measurements have been considered to monitor hybridization of single base mismatch (SBM) in synthetic oligonucleotides and single-nucleotide polymorphisms ApoE in real clinical genotypes. Obvious...

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PMID: 23714847
DOI: 10.1016/j.bios.2013.04.023

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