Article
DNA microarrays on nanoscale-controlled surface.
Nucleic acids research - 7 Jul 2005
Hong Bong Jin, Sunkara Vijaya, Park Joon Won
Abstract excerpt
We have developed new surface to ensure a proper spacing between immobilized biomolecules. While DNA microarray on this surface provided each probe DNA with ample space for hybridization with incoming target DNAs, the microarray showed enhanced discrimination efficiency for various types of single nucleotide polymorphism. The high discrimination efficiency holds for all tested cases (100:<1 for internal...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
