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Glutathione S-transferase mu locus: use of genotyping and phenotyping assays to assess association with lung cancer susceptibility.

Carcinogenesis - 1 Sept 1991

Zhong S, Howie A F, Ketterer B, Taylor J, Hayes J D, Beckett G J, Wathen C G, Wolf C R, Spurr N K

Abstract excerpt

In mammals, the cytosolic glutathione S-transferases (GSTs; EC 2.5.1.18) are a supergene family comprised of four multigene families, named alpha, mu, pi and theta. In man, within the mu class gene family there is a gene (the GSTmu 1 locus) that is polymorphic and is only expressed in 50-55% of individuals. It has previously been reported, using trans-stilbene oxide (tSBO) as a specific substrate for the...

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PMID: 1680031
DOI: 10.1093/carcin/12.9.1533

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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