Genotype and phenotype of glutathione S-transferase class mu isoenzymes mu and psi in lung cancer patients and controls.

Article

Genotype and phenotype of glutathione S-transferase class mu isoenzymes mu and psi in lung cancer patients and controls.

Cancer research - 1 Mar 1993

Brockmöller J, Kerb R, Drakoulis N, Nitz M, Roots I

Abstract excerpt

Glutathione S-transferase class mu (GSTM1) is known to detoxify certain carcinogens or their activated metabolites. In a previous study using phenotyping methods, individuals genetically devoid of this enzyme activity were significantly overrepresented among lung cancer patients compared to contr...

Topics

Adult
Aged
Aged, 80 and over
Alleles
Base Sequence
Female
Genotype
Glutathione Transferase
Humans
Isoenzymes
Lung Neoplasms
Male
Middle Aged
Molecular Sequence Data
Phenotype
Risk Factors

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