Article
Gene deficiency of glutathione S-transferase mu isoform associated with susceptibility to lung cancer in a Chinese population.
Cancer letters - 26 Feb 1997
Sun G F, Shimojo N, Pi J B, Lee S, Kumagai Y
Abstract excerpt
Increased lung cancer risk associated with genetic polymorphism of glutathione S-transferase (GST, EC 2.5.1.18) isozyme mu was examined in a Chinese population. A significantly higher proportion in lung cancer patients showed GST mu deficiency compared with control group (71.0% vs. 51.1%, P < 0.005). Although the susceptibility to lung cancer showing gene deletion for GST mu isoform in non-smoking group is not...
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