The glutathione S-transferase mu polymorphism as a marker for susceptibility to lung carcinoma.

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Article

The glutathione S-transferase mu polymorphism as a marker for susceptibility to lung carcinoma.

Cancer research - 15 May 1993

Nazar-Stewart V, Motulsky A G, Eaton D L, White E, Hornung S K, Leng Z T, Stapleton P, Weiss N S

Abstract excerpt

Glutathione S-transferase (GST) enzymes detoxify carcinogens in tobacco smoke. Interindividual variation in GST function may be related to differences in risk for smoking-related cancer. Leukocytes from 50% of Caucasians lack GST activity toward trans-stilbene oxide (TSO), due to a deletion of th...

Topics

Adult
Aged
Aged, 80 and over
Biomarkers, Tumor
Blotting, Southern
Female
Genetic Predisposition to Disease
Glutathione Transferase
Humans
Individuality
Isoenzymes
Leukocytes
Lung
Lung Neoplasms
Male
Middle Aged
Polymorphism, Genetic
Predictive Value of Tests

Source

Open in PubMed

Identifiers

PMID: 8485718

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8485718-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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