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Article

Glutathione S-transferase M1 polymorphism and the risk of lung cancer.

Anticancer research - 1 Jan 2000

Mohr Lawrence C, Rodgers J Keith, Silvestri Gerard A

Abstract excerpt

Glutathione S-transferases (GSTs) are a family of enzymes that detoxify hydrophobic electrophiles, including polycyclic aromatic hydrocarbon carcinogens that have been implicated in the pathogenesis of lung cancer. The GSTM1 gene within the mu class of human GSTs has been shown to be polymorphic, with individuals who are homozygous for a null allele having the GSTM1-null genotype. Individuals with the GSTM1-null...

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Source

Identifiers

PMID: 12894585

Genes

GSTM1
GSTM3
GSTP1
NAT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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