Article
The GSTM1 null genotype as a potential risk modifier for squamous cell carcinoma of the lung.
Carcinogenesis - 1 Jul 1993
Hirvonen A, Husgafvel-Pursiainen K, Anttila S, Vainio H
Abstract excerpt
The identification of genetic traits that predispose individuals to environmentally induced cancers is one of the challenges in the assessment of individual cancer risk. For this reason, individual variations in the expression of enzymes involved in biotransformation reactions have been extensively studied. One such polymorphic enzyme is GSTM1, which belongs to the class Mu of glutathione S-transferases (GSTs),...
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