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Article

Relationship between the GSTM1 genetic polymorphism and susceptibility to bladder, breast and colon cancer.

Carcinogenesis - 1 Sept 1993

Zhong S, Wyllie A H, Barnes D, Wolf C R, Spurr N K

Abstract excerpt

Mammalian cytosolic glutathione S-transferases (GSTs; EC 2.5.1.18) form a supergene family consisting of four distinct families, named alpha, mu, pi and theta. In humans one member of the mu class gene family (GSTM1) has been shown to be polymorphic and is only expressed in 55-60% of individuals. Previous studies have shown a possible link with the null phenotype and susceptibility to cancer, in particular to...

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Source

Identifiers

PMID: 8403204
DOI: 10.1093/carcin/14.9.1821

Genes

GSTM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Association of the GSTM1 null polymorphism with breast cancer in a Mexican population.Semantic proximity Read ↗

Polymorphic deletions of the GSTT1 and GSTM1 genes and susceptibility to bladder cancer.Semantic proximity Read ↗

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Glutathione S-transferase T1 and M1 genotypes in normal mucosa, transitional mucosa and colorectal adenocarcinoma.Semantic proximity Read ↗

The prognostic impact of GSTM1/GSTP1 genetic variants in bladder Cancer.Semantic proximity Read ↗

GSTM1 and GSTT1 polymorphisms are associated with increased bladder cancer risk: Evidence from updated meta-analysis.Semantic proximity Read ↗

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