Relationship between the GSTM1 genetic polymorphism and susceptibility to bladder, breast and colon cancer.

doi:10.1093/carcin/14.9.1821

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Article

Relationship between the GSTM1 genetic polymorphism and susceptibility to bladder, breast and colon cancer.

Carcinogenesis - 1 Sept 1993

Zhong S, Wyllie A H, Barnes D, Wolf C R, Spurr N K

Abstract excerpt

Mammalian cytosolic glutathione S-transferases (GSTs; EC 2.5.1.18) form a supergene family consisting of four distinct families, named alpha, mu, pi and theta. In humans one member of the mu class gene family (GSTM1) has been shown to be polymorphic and is only expressed in 55-60% of individuals....

Topics

Base Sequence
Breast Neoplasms
Colonic Neoplasms
Genetic Predisposition to Disease
Glutathione Transferase
Humans
Molecular Sequence Data
Polymerase Chain Reaction
Polymorphism, Genetic
Urinary Bladder Neoplasms

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