Article
Interindividual variability of canalicular ATP-binding-cassette (ABC)-transporter expression in human liver.
Hepatology (Baltimore, Md.) - 1 Jul 2006
Meier Yvonne, Pauli-Magnus Christiane, Zanger Ulrich M, Klein Kathrin, Schaeffeler Elke, Nussler Andreas K, Nussler Natascha, Eichelbaum Michel, Meier Peter J, Stieger Bruno
Abstract excerpt
Interindividual variability in hepatic canalicular transporter expression might predispose to the development of hepatic disorders such as acquired forms of intrahepatic cholestasis. We therefore investigated expression patterns of bile salt export pump (BSEP, ABCB11), multidrug resistance protein 3 (MDR3, ABCB4), multidrug resistance associated protein 2 (MRP2, ABCC2) and multidrug resistance protein 1 (MDR1,...
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