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Article

Mutations and polymorphisms in the bile salt export pump and the multidrug resistance protein 3 associated with drug-induced liver injury.

Pharmacogenetics and genomics - 1 Jan 2007

Lang Carmen, Meier Yvonne, Stieger Bruno, Beuers Ulrich, Lang Thomas, Kerb Reinhold, Kullak-Ublick Gerd A, Meier Peter J, Pauli-Magnus Christiane

Abstract excerpt

OBJECTIVES: Increasing evidence suggests that a genetically determined functional impairment of the hepatocellular efflux transporters bile salt export pump (BSEP, ABCB11) and multidrug resistance protein 3 (MDR3, ABCB4) play a pathophysiological role in the development of drug-induced liver inju...

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Share to ATP Binding Cassette Transporter, Subfamily B
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Source

Identifiers

PMID: 17264802
DOI: 10.1097/01.fpc.0000230418.28091.76

Genes

ABCB11
ABCB4

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17264802-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Mutations and polymorphisms in the bile salt export pump and the multidrug resistance protein 3 associated with drug-induced liver injury.PMID 17264802Read ↗

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