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Article

Genetic variations of the ABC transporter gene ABCB11 encoding the human bile salt export pump (BSEP) in a Japanese population.

Drug metabolism and pharmacokinetics - 1 Jan 2009

Kim Su-Ryang, Saito Yoshiro, Itoda Masaya, Maekawa Keiko, Kawamoto Manabu, Kamatani Naoyuki, Ozawa Shogo, Sawada Jun-ichi

Abstract excerpt

The bile salt export pump (BSEP) encoded by ABCB11 is located in the canalicular membrane of hepatocytes and mediates the secretion of numerous conjugated bile salts into the bile canaliculus. In this study, 28 ABCB11 exons (including non-coding exon 1) and their flanking introns were comprehensively screened for genetic variations in 120 Japanese subjects. Fifty-nine genetic variations, including 19 novel ones,...

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Source

Identifiers

PMID: 19571440
DOI: 10.2133/dmpk.24.277

Genes

ABCB11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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