Article
Genetic variations of bile salt transporters.
Drug discovery today. Technologies - 1 Jun 2014
Kubitz Ralf, Dröge Carola, Kluge Stefanie, Stindt Jan, Häussinger Dieter
Abstract excerpt
Bile salt transporters directly or indirectly influence biological processes through physicochemical or signalling properties of bile salts. The coordinated action of uptake and efflux transporters in polarized epithelial cells of the liver, biliary tree, small intestine and kidney determine bile salt concentrations in different compartments of the body. Genetic variations of bile salt transporters lead to...
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