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Article

Implication of the folate-methionine metabolism pathways in susceptibility to follicular lymphomas.

Blood - 1 Jul 2006

Niclot Sidonie, Pruvot Quentin, Besson Caroline, Savoy Daniel, Macintyre Elisabeth, Salles Gilles, Brousse Nicole, Varet Bruno, Landais Paul, Taupin Pierre, Junien Claudine, Baudry-Bluteau Dominique

Abstract excerpt

The incidence of follicular lymphoma (FL) in industrialized countries has been increasing since the 1950s. Polymorphisms in genes encoding key enzymes controlling folate-methionine metabolism, including methylenetetrahydrofolate reductase (MTHFR), methionine synthase (MS or MTR), serine hydroxymethyltransferase (SHMT), and thymidylate synthase (TS or TYMS), modify the risk of various cancers and possibly FL. This...

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Share to 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Glycine Hydroxymethyltransferase

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Share to Methylenetetrahydrofolate Reductase (NADPH2)

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Source

Identifiers

PMID: 16410450
DOI: 10.1182/blood-2005-04-1567

Genes

MTR
MTHFR
TYMS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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Implication of the folate-methionine metabolism pathways in susceptibility to follicular lymphomas.PMID 16410450Read ↗

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Methylenetetrahydrofolate reductase gene (MTHFR) polymorphisms and reduced risk of malignant lymphoma.Semantic proximity Read ↗

Polymorphisms and haplotypes in folate-metabolizing genes and risk of non-Hodgkin lymphoma.Semantic proximity Read ↗

Methylenetetrahydrofolate reductase gene polymorphisms association with the risk of follicular lymphoma: a meta-analysis.Semantic proximity Read ↗

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Associations between polymorphisms in the thymidylate synthase and serine hydroxymethyltransferase genes and susceptibility to malignant lymphoma.Semantic proximity Read ↗

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