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Article

Regulation of peroxisome proliferator-activated receptor-gamma in liver fibrosis.

American journal of physiology. Gastrointestinal and liver physiology - 1 Nov 2006

Yang Liu, Chan Che-Chang, Kwon Oh-Sang, Liu Songling, McGhee Jason, Stimpson Stephen A, Chen Lihong Z, Harrington W Wallace, Symonds William T, Rockey Don C

Abstract excerpt

The peroxisome proliferator-activated receptors (PPARs) impart diverse cellular effects in biological systems. Because stellate cell activation during liver injury is associated with declining PPARgamma expression, we hypothesized that its expression is critical in stellate cell-mediated fibrogenesis. We therefore modulated its expression during liver injury in vivo. PPARgamma was depleted in rat livers by using...

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Identifiers

PMID: 16798724
DOI: 10.1152/ajpgi.00124.2006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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