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Article

PPAR-gamma agonists inhibit profibrotic phenotypes in human lung fibroblasts and bleomycin-induced pulmonary fibrosis.

American journal of physiology. Lung cellular and molecular physiology - 1 May 2008

Milam Jami E, Keshamouni Venkateshwar G, Phan Sem H, Hu Biao, Gangireddy Srinivasa R, Hogaboam Cory M, Standiford Theodore J, Thannickal Victor J, Reddy Raju C

Abstract excerpt

Pulmonary fibrosis is characterized by alterations in fibroblast phenotypes resulting in excessive extracellular matrix accumulation and anatomic remodeling. Current therapies for this condition are largely ineffective. Peroxisome proliferator-activated receptor-gamma (PPAR-gamma) is a member of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18162602
DOI: 10.1152/ajplung.00333.2007
PMCID: PMC5926773

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18162602-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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