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Article

Adipogenic transcriptional regulation of hepatic stellate cells.

The Journal of biological chemistry - 11 Feb 2005

She Hongyun, Xiong Shigang, Hazra Saswati, Tsukamoto Hidekazu

Abstract excerpt

Hepatic stellate cells (HSC) undergo transdifferentiation (activation) from lipid-storing pericytes to myofibroblastic cells to participate in liver fibrogenesis. Our recent work demonstrates that depletion of peroxisome proliferator-activated receptor gamma (PPARgamma) constitutes one of the key molecular events for HSC activation and that ectopic expression of this nuclear receptor achieves the phenotypic...

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Identifiers

PMID: 15537655
DOI: 10.1074/jbc.M410078200

Genes

EBP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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