Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Pleiotropic actions of peroxisome proliferator-activated receptors in lipid metabolism and atherosclerosis.

Arteriosclerosis, thrombosis, and vascular biology - 1 May 2002

Barbier O, Torra I Pineda, Duguay Y, Blanquart C, Fruchart J-C, Glineur C, Staels B

Abstract excerpt

Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors activated by fatty acids and derivatives. Although PPARalpha mediates the hypolipidemic action of fibrates, PPARgamma is the receptor for the antidiabetic glitazones. PPARalpha is highly expressed in tissues such as liver, muscle, kidney, and heart, where it stimulates the beta-oxidative degradation of fatty acids. PPARgamma is...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arteriosclerosis
Share to Lipid Metabolism

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Nuclear Proteins

Share to Phenotype

Share to Receptors, Cytoplasmic and Nuclear

Share to Transcription Factors

Source

Identifiers

PMID: 12006382
DOI: 10.1161/01.atv.0000015598.86369.04

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Pleiotropic actions of peroxisome proliferator-activated receptors in lipid metabolism and atherosclerosis.PMID 12006382Read ↗

Peroxisome proliferator activated receptors and obesity.Semantic proximity Read ↗

Peroxisome proliferator-activated receptor gamma (PPARgamma) and its ligands: a review.Semantic proximity Read ↗

Peroxisome proliferator-activated receptors and the cardiovascular system.Semantic proximity Read ↗

PPARs and their Effects on the Cardiovascular SystemSemantic proximity Read ↗

Pleiotropic actions of PPAR gamma activators thiazolidinediones in cardiovascular diseases.Semantic proximity Read ↗

Roles of PPARα and PPARγ As Regulator of Free Fatty Acids in Nonalcoholic SteatohepatitisSemantic proximity Read ↗

PPARgamma in human and mouse physiology.Semantic proximity Read ↗

A glimpse of the connection between PPARγ and macrophageSemantic proximity Read ↗

PPARs: Regulators of Metabolism and As Therapeutic Targets in Cardiovascular disease. Part I: PPAR-αSemantic proximity Read ↗

International Union of Pharmacology. LXI. Peroxisome proliferator-activated receptors.Semantic proximity Read ↗

PPAR gamma as a metabolic regulator: insights from genomics and pharmacology.Semantic proximity Read ↗

Peroxisome proliferator-activated receptor-gamma calls for activation in moderation: lessons from genetics and pharmacology.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.