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Article

Role of Calcineurin in Stress Resistance, Morphogenesis, and Virulence of a Candida albicans Wild-Type Strain

21 Jun 2006

Abstract excerpt

By generating a calcineurin mutant of the Candida albicans wild-type strain SC5314 with the help of a new recyclable dominant selection marker, we confirmed that calcineurin mediates tolerance to a variety of stress conditions but is not required for the ability of C. albicans to switch to filamentous growth in response to hypha-inducing environmental signals. While calcineurin was essential for virulence of C....

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PMID: 16790813
DOI: 10.1128/iai.00142-06

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Source receipt: pubmed, retrieved 7 Sept 2026.

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