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Article

The connection between splicing and cancer.

Journal of cell science - 1 Jul 2006

Srebrow Anabella, Kornblihtt Alberto R

Abstract excerpt

Alternative splicing is a crucial mechanism for generating protein diversity. Different splice variants of a given protein can display different and even antagonistic biological functions. Therefore, appropriate control of their synthesis is required to assure the complex orchestration of cellular processes within multicellular organisms. Mutations in cis-acting splicing elements or changes in the activity of...

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Source

Identifiers

PMID: 16787944
DOI: 10.1242/jcs.03053

Genes

BRCA1
CDH17
KIT
KLF6
RAC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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