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Article

Significance of alternative splicing in cancer cells

22 Nov 2019

Abstract excerpt

OBJECTIVE: Alternative splicing can generate various structural and functional protein isoforms. Recently, accumulating evidence shows a relationship between alternative splicing and cancer. Cancer is a complex and chronic disease that involves malignant transformation. In this review, we consider alternative splicing events in relation to the hallmarks of cancer cells, and discuss current therapies to treat...

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PMID: 31764175
DOI: 10.1097/cm9.0000000000000542

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