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Article

Splice variants as cancer biomarkers.

Clinical biochemistry - 1 Jul 2004

Brinkman Brigitta M N

Abstract excerpt

Inherited and acquired changes in pre-mRNA splicing have been documented to play a significant role in human disease development and many cancer-associated genes are regulated by alternative splicing. Loss of fidelity, variation of the splicing process, even controlled switching to specific splicing alternatives may occur during tumor progression and could play a major role in carcinogenesis. Splice variants that...

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Identifiers

PMID: 15234240
DOI: 10.1016/j.clinbiochem.2004.05.015

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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