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Article

[Pre-mRNA alternative splicing in cancer: functional impact, molecular mechanisms and therapeutic perspectives].

Bulletin du cancer - 1 Sept 2006

Revil Timothée, Shkreta Lulzim, Chabot Benoît

Abstract excerpt

For most of the 25,000 human genes, the removal of introns by pre-messenger RNA splicing represents an essential step towards the production of functional messenger RNAs. Moreover, a majority of pre-messenger RNAs is alternatively spliced to yield different messenger RNAs. Cancer cells often display aberrant profiles of alternative splicing producing isoforms that can stimulate cell proliferation and migration or...

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PMID: 16980234

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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