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Phosphatidylinositol 4,5-bisphosphate Impacts Extracellular Vesicle Shedding from <i>C. elegans</i> Ciliated Sensory Neurons

2025-02-08

Abstract excerpt

Small secreted extracellular vesicles (EVs) mediate intercellular transport of bioactive macromolecules. How the membrane lipid phosphatidylinositol 4,5-bisphosphate (PI(4,5)P 2 ), which plays a critical role in many cellular processes, impacts EV biogenesis is unclear. The primary cilium, a sensory organelle protruding from most non-dividing cells, transmits signals by shedding EVs called ectosomes. Here, we alt...

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Identifiers and source

Literature Corpus work
f7aec244-2dcd-5d01-89d2-7ffb1788e644
DOI
10.1101/2025.02.05.636762
Open publication

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Phosphatidylinositol 4,5-bisphosphate Impacts Extracellular Vesicle Shedding from <i>C. elegans</i> Ciliated Sensory NeuronsDOI 10.1101/2025.02.05.636762
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