Isolation of temperature-sensitive DNA polymerase III from Saccharomyces cerevisiae cdc2-2.

doi:10.1021/bi00246a030

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Article

Isolation of temperature-sensitive DNA polymerase III from Saccharomyces cerevisiae cdc2-2.

Biochemistry - 13 Aug 1991

Blank A, Loeb L A

Abstract excerpt

DNA polymerase III of the yeast Saccharomyces cerevisiae has been reported to be encoded at the CDC2 locus based on two observations. First, the CDC2 gene has homology to known DNA polymerase genes [Boulet et al. (1989) EMBO J. 8, 1849-1854], and second, the mutants cdc2-1 and cdc2-2 yield little...

Topics

Alleles
DNA Polymerase III
Fungal Proteins
Genes, Fungal
Kinetics
Mutation
Nuclear Proteins
Proliferating Cell Nuclear Antigen
Saccharomyces cerevisiae

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