Nucleotide sequence and characterization of temperature-sensitive pol1 mutants of Saccharomyces cerevisiae.

doi:10.1016/0378-1119(90)90444-v

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Article

Nucleotide sequence and characterization of temperature-sensitive pol1 mutants of Saccharomyces cerevisiae.

Gene - 31 May 1990

Lucchini G, Muzi Falconi M, Pizzagalli A, Aguilera A, Klein H L, Plevani P

Abstract excerpt

We have analyzed the effects of temperature-sensitivity (ts)-conferring mutations in the Saccharomyces cerevisiae DNA polymerase I-encoding gene on cell growth, in vivo DNA synthesis, intrachromosomal gene conversion and pop-out recombination. Also, we have identified the molecular defect respons...

Topics

Amino Acid Sequence
Cell Division
DNA Polymerase I
DNA, Fungal
Fungal Proteins
Mitosis
Molecular Sequence Data
Mutation
Recombination, Genetic
Saccharomyces cerevisiae
Temperature

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