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Article

Nucleotide sequence and characterization of temperature-sensitive pol1 mutants of Saccharomyces cerevisiae.

Gene - 31 May 1990

Lucchini G, Muzi Falconi M, Pizzagalli A, Aguilera A, Klein H L, Plevani P

Abstract excerpt

We have analyzed the effects of temperature-sensitivity (ts)-conferring mutations in the Saccharomyces cerevisiae DNA polymerase I-encoding gene on cell growth, in vivo DNA synthesis, intrachromosomal gene conversion and pop-out recombination. Also, we have identified the molecular defect responsible for the ts phenotype. Two mutant alleles (cdc17-1, cdc17-2) were originally identified as cell-cycle mutations,...

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Identifiers

PMID: 2199334
DOI: 10.1016/0378-1119(90)90444-v

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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