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Article

Assessment of microsatellite instability in very small microdissected samples and in tumor samples that are contaminated with normal DNA.

Diagnostic molecular pathology : the American journal of surgical pathology, part B - 1 Jun 2006

Trusky Cynthia L, Sepulveda Antonia R, Hunt Jennifer L

Abstract excerpt

Microsatellite instability (MSI) testing is important for the management of young patients with colonic adenocarcinoma. Biopsies can be small and can be contaminated by normal cells. It is not known how sample size or contamination by non-neoplastic cell populations affects the interpretation of MSI assays. Serial microdissection targets (0.75 to 5.5 mm) were obtained from cases with high-level MSI. Polymerase...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 16778585
DOI: 10.1097/00019606-200606000-00001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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