Article
GABA(A) receptor beta isoform protein expression in human alcoholic brain: interaction with genotype.
Neurochemistry international - 1 Nov 2006
Buckley S Tracey, Foley Philomena F, Innes David J, Loh El-Wui, Shen Yi, Williams Susan M, Harper Clive G, Tannenberg Anthony E G, Dodd Peter R
Abstract excerpt
Chronic alcohol misuse by human subjects leads to neuronal loss in regions such as the superior frontal cortex. Reduced GABA transmission may mediate this. The expression of GABA(A) receptor beta(1), beta(2), and beta(3) isoform proteins was analyzed by western blotting in vulnerable (superior fr...
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