D2 dopamine receptor and GABA(A) receptor beta3 subunit genes and alcoholism.

doi:10.1016/s0165-1781(98)00084-5

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Article

D2 dopamine receptor and GABA(A) receptor beta3 subunit genes and alcoholism.

Psychiatry research - 16 Nov 1998

Noble E P, Zhang X, Ritchie T, Lawford B R, Grosser S C, Young R M, Sparkes R S

Abstract excerpt

As the dopaminergic and GABAergic systems have been implicated in alcohol-related behaviors, variants of the D2 dopamine receptor (DRD2) and GABA(A) receptor beta3 subunit (GABRB3) genes were determined in a population-based association study of Caucasian non-alcoholic and alcoholic subjects. In...

Topics

Adult
Alcoholism
Alleles
Australia
Female
Gene Frequency
Genetic Predisposition to Disease
Genetic Variation
Genotype
Humans
Male
Middle Aged
Models, Genetic
Prognosis
Receptors, Dopamine D2
Receptors, GABA-A
Risk

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