Article
Sex differences in GABAA receptor subunit transcript expression are mediated by genotype in subjects with alcohol-related cirrhosis of the liver.
Genes, brain, and behavior - 1 Apr 2022
Ashton Madeline K, Rueda André V L, Ho Ada M-C, Noor Aizin Noradibah Arina Binte M, Sharma Hansa, Dodd Peter R, Stadlin Alfreda, Camarini Rosana
Abstract excerpt
Male and female human subjects show contrasting propensities to misuse drugs of addiction, including alcohol. These differences lead to different psychological and neurological consequences, such as the likelihood of developing dependence. The pattern and extent of brain damage in alcohol-use disorder cases also varies with comorbid disease. To explore mechanisms that might underlie these outcomes, we used...
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