Article
Hypertrophy of cerebral arterioles in mice deficient in expression of the gene for CuZn superoxide dismutase.
Stroke - 1 Jul 2006
Baumbach Gary L, Didion Sean P, Faraci Frank M
Abstract excerpt
BACKGROUND AND PURPOSE: Reactive oxygen species are believed to be an important determinant of vascular growth. We examined effects of genetic deficiency of copper-zinc superoxide dismutase (CuZnSOD; SOD1) on structure and function of cerebral arterioles. METHODS: Systemic arterial pressure (SAP) and cross-sectional area of the vessel wall (CSA) and superoxide (O2-) levels (relative fluorescence of ethidium...
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