Article
Selective impairment of blood pressure reduction by endothelial nitric oxide synthase dimer destabilization in mice.
Journal of hypertension - 1 Jan 2017
Suvorava Tatsiana, Pick Stephanie, Kojda Georg
Abstract excerpt
OBJECTIVES: Endothelial dysfunction and oxidative stress are associated with hypertension but whether endothelial superoxide may play a role in the early development of essential hypertension remains uncertain. We investigated whether endothelial nitric oxide synthase (eNOS)-derived endothelial oxidative stress is involved in the regulation of SBP. METHODS: Wild-type eNOS [mice with endothelium-specific...
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