Article
A tutorial on statistical methods for population association studies.
Nature reviews. Genetics - 1 Oct 2006
Balding David J
Abstract excerpt
Although genetic association studies have been with us for many years, even for the simplest analyses there is little consensus on the most appropriate statistical procedures. Here I give an overview of statistical approaches to population association studies, including preliminary analyses (Hardy-Weinberg equilibrium testing, inference of phase and missing data, and SNP tagging), and single-SNP and multipoint...
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