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Article

Association of IL13 with total IgE: evidence against an inverse association of atopy and diabetes.

The Journal of allergy and clinical immunology - 1 Jun 2006

Maier Lisa M, Howson Joanna M M, Walker Neil, Spickett Gavin P, Jones Richard W, Ring Susan M, McArdle Wendy L, Lowe Christopher E, Bailey Rebecca, Payne Felicity, Todd John A, Strachan David P

Abstract excerpt

BACKGROUND: Atopic illnesses, related to high circulating IgE levels, and the autoimmune disease type 1 diabetes, have been reported to be inversely associated. One possible explanation is that susceptibility alleles for one disease provide protection for the other. OBJECTIVE: Using the largest sample sizes reported so far for the identification of genetic determinants of circulating IgE levels, we investigated...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Diabetes Mellitus, Type 1

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Share to Interleukin-13

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 16750991
DOI: 10.1016/j.jaci.2005.12.1354

Genes

CTLA4
PTPN22

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Association of IL13 with total IgE: evidence against an inverse association of atopy and diabetes.PMID 16750991Read ↗

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