Article
Gene-gene interactions between candidate gene polymorphisms are associated with total IgE levels in Korean children with asthma.
The Journal of asthma : official journal of the Association for the Care of Asthma - 1 Apr 2012
Choi Won-Ah, Kang Mi-Jin, Kim Young-Joon, Seo Ju-Hee, Kim Hyung-Young, Kwon Ji-Won, Yu Jinho, Park Seoung-Ju, Lee Yong-Chul, Hong Soo-Jong
Abstract excerpt
OBJECTIVE: To investigate associations between total serum immunoglobulin E (IgE) levels and single nucleotide polymorphisms (SNPs) from eight candidate genes (IL-4 rs2243250, IL-4Rα rs1805010, IL-13 rs20541, IL-13Rα1 rs2495636, CD14 rs2569190, tumor necrosis factor-alpha (TNF-α) , cytotoxic T lymphocyte-associated antigen (CTLA4) , FCER1B ) in children with asthma and to evaluate...
