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Article

Current concepts of IgE regulation and impact of genetic determinants

1 Jun 2012

Abstract excerpt

Immunoglobulin E (IgE) mediated immune responses seem to be directed against parasites and neoplasms, but are best known for their involvement in allergies. The IgE network is tightly controlled at different levels as outlined in this review. Genetic determinants were suspected to influence IgE regulation and IgE levels considerably for many years. Linkage and candidate gene studies suggested a number of loci and...

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Identifiers

PMID: 22909159
DOI: 10.1111/j.1365-2222.2011.03953.x

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