Article
Associations between total serum IgE levels and the 6 potentially functional variants within the genes IL4, IL13, and IL4RA in German children: the German Multicenter Atopy Study.
The Journal of allergy and clinical immunology - 1 Aug 2003
Liu Xin, Beaty Terri H, Deindl Philipp, Huang Shau-Ku, Lau Susanne, Sommerfeld Christine, Fallin M Daniele, Kao W H Linda, Wahn Ulrich, Nickel Renate
Abstract excerpt
BACKGROUND: Increased total serum IgE levels are a common characteristic of atopic disorders. Six potentially functional variants, including C-590T in the IL4 gene, C-1055T and Arg130Gln in the IL13 gene, and Ile50Val, Ser478Pro, and Gln551Arg in the IL4RA gene, have been evaluated for their involvement in the control of total serum IgE levels and related atopic disorders, but the results of these studies have...
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