Article
An IL13 coding region variant is associated with a high total serum IgE level and atopic dermatitis in the German multicenter atopy study (MAS-90).
The Journal of allergy and clinical immunology - 1 Jul 2000
Liu X, Nickel R, Beyer K, Wahn U, Ehrlich E, Freidhoff L R, Björkstén B, Beaty T H, Huang S K
Abstract excerpt
BACKGROUND: Allergic diseases are one of the major causes of morbidity in the developed countries today, and the prevalence of these diseases is increasing steadily. Study of total serum gE level is important in understanding the genetics of allergic iseases because IgE levels are considered to be a crucial pathogenic component. IL-13 plays an important role in the induction of IgE synthesis and in the...
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