Article
Polymorphisms in IL13, total IgE, eosinophilia, and asthma exacerbations in childhood.
The Journal of allergy and clinical immunology - 1 Jul 2007
Hunninghake Gary M, Soto-Quirós Manuel E, Avila Lydiana, Su Jessica, Murphy Amy, Demeo Dawn L, Ly Ngoc P, Liang Catherine, Sylvia Jody S, Klanderman Barbara J, Lange Christoph, Raby Benjamin A, Silverman Edwin K, Celedón Juan C
Abstract excerpt
BACKGROUND: It is unclear whether single nucleotide polymorphisms (SNPs) in the gene for IL-13 (IL13) influence asthma severity and/or asthma morbidity. OBJECTIVES: To examine the relation between IL13 SNPs and asthma-related phenotypes in 2 independent populations. METHODS: We used family-based methods to test for association between SNPs in IL13 and asthma-related phenotypes in Costa Rican children with asthma....
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