[Allelic chromosomal deletion using microsatellite polymorphism--the clue to the positional cloning of the tumor suppressor genes responsible for gastric carcinoma].

Article

[Allelic chromosomal deletion using microsatellite polymorphism--the clue to the positional cloning of the tumor suppressor genes responsible for gastric carcinoma].

Nihon rinsho. Japanese journal of clinical medicine - 1 Apr 1996

Sato J, Fukutomi H

Abstract excerpt

Cancers are caused by an accumulation of multiple genetic lesions that we are now beginning to understand. Gastric cancer has a different morphological appearance, ability to invade or metastasize, and response to treatment. The pattern of loss of heterozygosity is similar, but not necessarily th...

Topics

Alleles
Cloning, Molecular
Gene Deletion
Genes, Tumor Suppressor
Heterozygote
Humans
Microsatellite Repeats
Stomach Neoplasms

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.