Article
Association analysis of delta-opioid receptor gene polymorphisms in methamphetamine dependence/psychosis.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Jul 2006
Kobayashi Hideaki, Hata Harumi, Ujike Hiroshi, Harano Mutsuo, Inada Toshiya, Komiyama Tokutaro, Yamada Mitsuhiko, Sekine Yoshimoto, Iwata Nakao, Iyo Masaomi, Ozaki Norio, Itokawa Masanari, Naka Maki, Ide Soichiro, Ikeda Kazutaka, Numachi Yohtaro, Sora Ichiro
Abstract excerpt
The role of the delta-opioid receptor (OPRD1) in methamphetamine (MAP) addiction was investigated using association analysis between OPRD1 gene polymorphisms and MAP dependence/psychosis. DNA samples from Japanese patients with MAP dependence/psychosis were analyzed to find polymorphisms in OPRD1 gene exons and exon-intron boundaries. One novel single nucleotide polymorphism (SNP) in intron 1 and two SNPs in exon...
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