Article
No association for D2 and D4 dopamine receptor polymorphisms and methamphetamine abuse in Chinese males.
Psychiatric genetics - 1 Mar 2002
Tsai Shih-Jen, Cheng Chih-Ya, Shu Li-Ren Remus, Yang Chin-Yi, Pan Chen-Wei, Liou Ying-Jay, Hong Chen-Jee
Abstract excerpt
The D2 and D4 dopamine receptors (DRD2 and DRD4) play major roles in the central effects of psychostimulants and in the reward system. Previous studies, although not all, have demonstrated associations between the DRD2 TaqI and the DRD4 exon III variable number tandem repeat (VNTR) polymorphisms and substance dependence. For this study, we have investigated the associations between these two polymorphisms and...
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