Article
Association study between brain-derived neurotrophic factor gene polymorphisms and methamphetamine abusers in Japan.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Jan 2005
Itoh Kanako, Hashimoto Kenji, Shimizu Eiji, Sekine Yoshimoto, Ozaki Norio, Inada Toshiya, Harano Mutsuo, Iwata Nakao, Komiyama Tokutaro, Yamada Mitsuhiko, Sora Ichiro, Nakata Kenji, Ujike Hiroshi, Iyo Masaomi
Abstract excerpt
Several lines of evidence suggest that genetic factors might contribute to drug abuse vulnerability. Recent genomic scans for association demonstrated that the brain-derived neurotrophic factor (BDNF) gene was associated with drug abuse vulnerability. In this study, we analyzed association of two BDNF gene single nucleotide polymorphisms (SNPs), 132C > T (C270T named formerly) in the noncoding region of exon V...
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