Article
Cytokine polymorphisms associated with carotid intima-media thickness in stroke patients.
Stroke - 1 Jul 2006
Brenner David, Labreuche Julien, Touboul Pierre-Jean, Schmidt-Petersen Klaus, Poirier Odette, Perret Claire, Schönfelder Jacqueline, Combadière Christophe, Lathrop Mark, Cambien François, Brand-Herrmann Stefan-Martin, Amarenco Pierre
Abstract excerpt
BACKGROUND AND PURPOSE: Carotid intima-media thickness (IMT) reflects generalized atherosclerosis and is predictive of future vascular events. Evidence exists that carotid IMT is heritable, and genetic studies can provide clues in the pathogenesis of atherosclerosis. METHODS: We recruited 470 white ischemic stroke patients, measured common carotid artery (CCA) IMT, and analyzed 54 polymorphisms with suspected...
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